Student Research Projects from Fall 2010
In Fall 2010, five research teams of four students each were challenged to propose and pursue a single focused research project for the semester. All students picked a genetic/gene-linked disease and designed PCR-based
diagostic assays for mutations known to cause that disease. Students chose to work on Breast Cancer, Tay Sachs Disease, Crohn's Disease, Hemophilia and PKU. Student teams pursued a 14-week investigation and
presented their findings in various forms (web sites, interviews, talks and multiple drafts of a scientific manuscript along the way). Each group was required to submit their final manuscript to the journal ReCUR as well as will present them at the 5th Annual Briggs Research Symposium as either posters or talks.
Student websites reporting their findings at the end of the independent investigations from Fall Semester 2010
Breast Cancer: PCR detection of 5382insc Mutation and View of Genetic Testing.
Crohn's Disease: CARD15 gene mutation detection by AS-PCR
Hemophilia: Utilizing Custom Oligonucleotides to Diagnose Hemophilia A
PKU: AS-PCR of CALU-3 DNA for diagnosing Phenylketonuria mutation R408W
Tay Sachs Disease: PCR amplification detecting 1278insTATC mutation
and analysis of Tay-Sachs handicaps
